UA RABI-20 Tablet
UA RABI-20 Tablets
(Rabeprazole Sodium 20 mg)
Product Overview
UA RABI-20 is a proton pump inhibitor (PPI) containing Rabeprazole Sodium 20 mg, designed to effectively reduce gastric acid secretion. It provides rapid relief and long-lasting control of acid related disorders such as GERD, acid reflux, peptic ulcer disease, and erosive esophagitis.
Composition:
- Each enteric-coated tablet contains: Rabeprazole Sodium IP – 20 mg
Pharmacological Class
- Class: Proton Pump Inhibitor (PPI)
- ATC Code: A02BC04
Mechanism of Action
Rabeprazole selectively inhibits the H⁺/K⁺-ATPase enzyme system (the gastric proton pump) in the parietal cells of the stomach.
- Blocks the final step of acid production
- Reduces both basal and stimulated gastric acid secretion
- Promotes healing of acid-related mucosal damage
Clinical Indications
UA RABI-20 is indicated for:
- Gastroesophageal Reflux Disease (GERD)
- Duodenal and Gastric Ulcers
- Zollinger–Ellison Syndrome
- Erosive Esophagitis
- Dyspepsia and Acid Peptic Disorders
- Adjuvant therapy with antibiotics for H. pylori eradication
Dosage & Administration:
- Recommended Dose: 20 mg once daily
- Route: Oral
- To be taken before meals (preferably in the morning)
- Duration: As directed by the physician, based on indication and patient response
Onset & Duration of Action
- Onset: Within 1 hour
- Peak effect: 2–4 hours
- Duration: Up to 24 hours of acid suppression
Contraindications:
- Hypersensitivity to Rabeprazole or any component of the formulation
- Severe hepatic impairment (use with caution)
Adverse Effects :
Generally well tolerated. Possible mild side effects include:
- Headache, dizziness
- Nausea, diarrhea, abdominal pain
- Flatulence or dry mouth
Precautions:
- Evaluate for gastric malignancy before initiating therapy.
- Use with caution in patients with liver disease.
- Prolonged therapy may cause hypomagnesemia or vitamin B12 deficiency
Storage:
Store in a cool, dry place below 25 °C, protected from moisture and direct sunlight. Keep out of reach of children.
Packaging:
- UA RABI-20 is available in Alu-Alu strips of 10 tablets per strip.
Key Benefits:
- Rapid & sustained acid control
- Promotes ulcer healing
- Reduces reflux symptoms
- Excellent patient compliance
